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Figure 2 | Cell Division

Figure 2

From: Structure-function analysis of the retinoblastoma tumor suppressor protein – is the whole a sum of its parts?

Figure 2

Commonly used RB-1 mutations and pRB domain structure. The open reading frame of pRB is shown along with the locations of the A and B parts of the pocket. Arrows indicate the positions and alterations found in commonly studied low penetrance and high penetrance mutant alleles. Below the open reading frame, structural regions of pRB are identified along with their approximate locations.

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