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Table 3 Anoxia sensitivity to assay spindle checkpoint activity

From: Genetic analysis of the spindle checkpoint genes san-1, mdf-2, bub-3 and the CENP-F homologues hcp-1 and hcp-2 in Caenorhabditis elegans

Genotype

Anoxia viability a

  
 

Hatch (%)

Adulthood (%)

No.

Wild-type

99.2 ± 1.1

99.0 ± 1.1

511

san-1(ok1580)

77.3 ± 8.4

42.7 ± 21.4 (P < .014)

482

bub-3(RNAi)

90.2 ± 3.1

81.0 ± 12.0 (P < .053)

481

hcp-1(RNAi)

92.6 ± 8.9

92.3 ± 8.5

230

  1. aAnimals were assayed for sensitivity to 1 day of anoxia by determining the percentage of anoxia exposed embryos that are able to hatch and develop to adulthood. Four independent experiments with a total number of embryos assayed (No.).
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Cell Division

ISSN: 1747-1028

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