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Table 3 Anoxia sensitivity to assay spindle checkpoint activity

From: Genetic analysis of the spindle checkpoint genes san-1, mdf-2, bub-3 and the CENP-F homologues hcp-1 and hcp-2 in Caenorhabditis elegans

Genotype Anoxia viability a   
  Hatch (%) Adulthood (%) No.
Wild-type 99.2 ± 1.1 99.0 ± 1.1 511
san-1(ok1580) 77.3 ± 8.4 42.7 ± 21.4 (P < .014) 482
bub-3(RNAi) 90.2 ± 3.1 81.0 ± 12.0 (P < .053) 481
hcp-1(RNAi) 92.6 ± 8.9 92.3 ± 8.5 230
  1. aAnimals were assayed for sensitivity to 1 day of anoxia by determining the percentage of anoxia exposed embryos that are able to hatch and develop to adulthood. Four independent experiments with a total number of embryos assayed (No.).