Figure 1From: Insights from mouse models into human retinoblastoma Normal retina and retinoblastoma (A) Thin section of normal murine retina with outer nuclear (ONL), inner nuclear layer (INL) and ganglion cell layer (GCL) shown. (B) Hematoxylin and Eosin (H+E) stain of human retinoblastoma with neuroblastic differentiation and Homer-Wright (HW) rosettes. (C) H+E staining of human retinoblastoma exhibiting Flexner-Wintersteiner (FW) rosettes. Inset: M-opsin immunostaining showing evidence of cone differentiation. (D) H+E of primary murine retinoblastoma lacking Rb and p130 with Homer-Wright rosettes indicated.Back to article page