Figure 2From: Real-time in vivo imaging of p16Ink4agene expression: a new approach to study senescence stress signaling in living animals Real-time bioluminescence imaging of p16INK4a gene expression during aging process in vivo. The same p16-luc mice were subjected to noninvasive BLI throughout their entire life span. The level of bioluminescent signals is significantly increased throughout the body during aging.Back to article page