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Table 2 Combined disruption of Dido and DNA-PKcs.

From: Merotelic attachments and non-homologous end joining are the basis of chromosomal instability

DNA-PKcs Dido N° pups (expected) N° pups (observed)
+/+ +/+ 60.25 100
+/+ +/neo 120.50 162
+/+ neo/neo 60.25 22
+/- +/+ 120.50 122
+/- +/neo 241.00 273
+/- neo/neo 120.50 40
-/- +/+ 60.25 56
-/- +/neo 120.50 169
-/- neo/neo 60.25 20
Total 964 964
  1. Mice heterozygous for Dido and DNA-PKcs were crossed and all viable pups were genotyped. Whereas the numbers of wild-type, heterozygous and DNA-PKcs mutant mice born are as expected, Dido and Dido DNA-PKcs mutant mouse numbers were below the expected frequency.