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Figure 2 | Cell Division

Figure 2

From: One-hit wonders of genomic instability

Figure 2

Failure to resolve links/locks between sister chromatids leads to anaphase chromosomal breaks in higher eukaryotes. Sister chromatids have differential color coding. DNA is represented by dotted lines, chromatin - by semitransparent circles, kinetochores - hexagons (with attached microtubules in mitosis), centromeric chromatin - semitransparent circles color-coordinated with corresponding kinetochores. Padlocks represent centromeric and arm sites where sister chromatids are attached to each other.

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