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Figure 7 | Cell Division

Figure 7

From: One-hit wonders of genomic instability

Figure 7

DNA underreplication may result in chromosomal breaks in higher cells. It is likely that yeast, due to their single-microtubule kinetochores, do not sustain substantial number of DSB as a result of chromatid bridging, opting for nondisjunction instead. It is likely, however, that human chromosomes would break, if underreplication zones are still present in anaphase.

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