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Table 2 Quantitation of phenotypic abnormalities upon hos2 or HDAC3 over-expression from the nmt1 promoter in the absence of thiamine

From: A conserved histone deacetylase with a role in the regulation of cytokinesis in Schizosaccharomyces pombe

Morphological Abnormality

pREP1

pREP1-hos2

pREP1-HDAC3

Normal

> 99%

52%

54%

Rounded/Depolarized

< 1%

26.5%

29%

Misplaced septa

<1%

9%

5%

Excessive/Misplaced septal deposits

0

6%

6%

Multiple septa

0

2%

2%

Elongated with multiple aberrant deposits of septal material

0

3%

2%

Elongated and Branched

0

1.5%

1.5%