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Table 1 Differential influence of Cdk2 loss on OPC

From: Differential requirement of cyclin-dependent kinase 2 for oligodendrocyte progenitor cell proliferation and differentiation

 

Physiological condition

Pathological condition

 

SVZ

CC

SVZ

CC

Proliferation

↓

NO

↓

↓

Differentiation

↑

NO

↑

↑

Myelination/ remyelination

NC

NO

NC

↑

  1. The pathological condition concerns corpus callosum LPC-induced demyelination. SVZ subventricular zone; CC corpus callosum; NO not observed; NC not concerned
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Cell Division

ISSN: 1747-1028

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