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Table 2 Ten most down- or up-regulated genes in CCRF-CEM cells after treatment guieranone A

From: Cytotoxicity, anti-angiogenic, apoptotic effects and transcript profiling of a naturally occurring naphthyl butenone, guieranone A

ID Symbol Description Fold Change
Up-regulated genes   
160092 HSPA6 heat shock 70 kDa protein 6 (HSP70B) 11.43
290730 HIST1H2BD histone cluster 1, H2bd 8.00
7160239 FOSB FBJ murine osteosarcoma viral oncogene homolog B 5.39
1820592 HIST2H2AA4 histone cluster 2, H2aa4 4.45
20129 CD52 CD52 molecule 4.16
610451 HIST2H2AA4 histone cluster 2, H2aa4 4.07
6510367 JUN jun oncogene 3.86
6660601 HMOX1 heme oxygenase (decycling) 1 3.64
1500600 RAB37 RAB37, member RAS oncogene family 3.34
6860072 TRAPPC6A trafficking protein particle complex 6A 3.29
Down-regulated genes   
2850020 DHRS2 dehydrogenase/reductase (SDR family) member 2 −4.17
3420400 KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) −4.18
4230196 KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) −4.48
460286 THOC4 THO complex 4 −4.50
4390315 HNRNPA1P2 heterogeneous nuclear ribonucleoprotein A1 pseudogene 2 −4.77
2750719 DDX21 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 −4.91
4890671 DHRS2 dehydrogenase/reductase (SDR family) member 2 −5.68
4880646 ACTBL3 actin, beta-like 3 −5.70
3940592 PGAM1 phosphoglycerate mutase 1 (brain) −5.76
5270730 ACTB actin, beta −6.50
  1. *Full list of gene in Supplementary Material.