Therapeutic targeting of cancer cell cycle using proteasome inhibitors

Cell Division

Table 1 List of proteasome inhibitors natural and synthetic in pre-clinical studies and clinical trials

FDA approved ^*/ In Clinical trials		In preclinical Studies
Synthetic	Natural	Synthetic	Natural
Bortezomib^* [9]	NPI-0052 [13]	CEP-18770 [12]	Celastrol [14]
Carfilzomib (PR-171) [16]			Shikonin [16]
MLN9708 [16]			EGCG [18]
			Curcumin [19]

ISSN: 1747-1028