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Table 1 List of proteasome inhibitors natural and synthetic in pre-clinical studies and clinical trials

From: Therapeutic targeting of cancer cell cycle using proteasome inhibitors

FDA approved */ In Clinical trials In preclinical Studies
Synthetic Natural Synthetic Natural
Bortezomib* [9] NPI-0052 [13] CEP-18770 [12] Celastrol [14]
Carfilzomib (PR-171) [16]    Shikonin [16]
MLN9708 [16]    EGCG [18]
    Curcumin [19]