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Figure 1 | Cell Division

Figure 1

From: Kinetics of DNA methylation inheritance by the Dnmt1-including complexes during the cell cycle

Figure 1

Dynamic of the formation and of the recruitment on DNA of the Dnmt1/PCNA-including complexes during the cell cycle. (A) ApoTome view of the Dnmt1/PCNA dots in U251 cells during the different phases of the cell cycle. Red dots symbolize Dnmt1/PCNA dots. Nucleus/DNA are stained in blue via the use of DAPI. Graph (mean ± SEM) illustrating the number of Dnmt1/PCNA dots per nucleus in U251 cells during the different phases of the cell cycle. The number of Dnmt1/PCNA interactions is calculated from the analysis of, at least, 50 nucleus in three independent experimentations. (B) Graph (mean ± SEM) illustrating the number of Dnmt1/UHRF1 interactions per nucleus in U251 cells during the different phases of the cell cycle. The number of Dnmt1/UHRF1 interactions is calculated from the analysis of, at least, 50 nucleus in three independent experimentations.

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