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Figure 5 | Cell Division

Figure 5

From: The role of β-adrenergic receptor signaling in the proliferation of hemangioma-derived endothelial cells

Figure 5

Role of cAMP production and VEGFR-2 and ERK activation on ISO-induced cell proliferation. HemECs were pre-treated with the cAMP antagonist, Rp-cAMP (10 μM), the VEGFR-2 inhibitor, PTK787 (10 μM), or the MAPK kinase inhibitor, U0126 (1 μM), for 1 h, incubated with 1 μM ISO for 12 h, and pulsed with 1:2,000 BrdU for 18 h. The results are shown as the mean ± SD of triplicate assays from one of three identical experiments. * P<0.05 when compared with the ISO-untreated control, P<0.05 when compared with the ISO-treated control.

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