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Table 2 IC 50 of irradiation in breast cancer cell lines with CDK2 or CDK4 knockdown

From: Silencing CDK4 radiosensitizes breast cancer cells by promoting apoptosis

Cell line Vector IC 50
Est. (SE) P value 1
MCF10A pLKO.1 1.76 (0.106) -
  shCDK2 1.75 (0.103) 0.943
  shCDK4 1.34 (0.076) 0.005
MDA-MB-231 pLKO.1 1.89 (0.141) -
  shCDK2 2.15 (0.158) 0.197
  shCDK4 1.27 (0.096) 0.003
HCC1806 pLKO.1 1.95 (0.149) -
  shCDK2 2.14 (0.173) 0.364
  shCDK4 0.85 (0.078) <0.001
MDA-MB-468 pLKO.1 2.04 (0.139) -
  shCDK2 2.27 (0.156) 0.252
  shCDK4 1.25 (0.093) <0.001
HCC1954 pLKO.1 2.99 (0.301) -
  shCDK4 2.02 (0.160) 0.013
  1. 1The p value is based on the comparisons with pLKO.1 group within each cell line.