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Table 4 Comparison of phospho-Histone 3 between control (pLKO.1) and treatment (shCDK4) groups

From: Silencing CDK4 radiosensitizes breast cancer cells by promoting apoptosis

Cell line Vector 0 Gy 2 Gy 4 Gy
Mean* std P-value† Mean std P-value† Mean std P-value†
MCF10A pLKO.1 1.229 0.530 0.145 1.737 0.278 0.277 0.823 0.587 0.168
shCDK4 2.001 0.961 1.560 0.385 1.498 0.891
MDA-MB-468 pLKO.1 0.476 0.555 0.462 0.808 0.171 0.256 0.799 0.221 0.249
shCDK4 0.509 0.077 0.654 0.330 0.979 0.359
MDA-MB-231 pLKO.1 0.168 0.160 0.324 0.170 0.176 0.084 0.060 0.104 0.181
  shCDK4 0.342 0.593   0 0   0.257 0.315  
  1. * Mean (standard deviation) of % of phospho-Histone 3 positive cells.
  2. † P-value is for comparing in the mean between control and treatment groups in each irradiation dosage.