Figure 1From: Rad53 homologue forkhead-associated kinase A (FhkA) and Ca2+-binding protein 4a (CBP4a) are nucleolar proteins that differentially redistribute during mitosis in Dictyostelium Domain structure diagram of FhkA and CBP4a. (A) FhkA (Rad53 in yeast, Chk2 in humans) possesses several putative FHA domains (asterisk indicates verified domains [47, 48]). Putative NLSs and the antigen site for anti-FhkA are indicated. Numbers represent amino acid position. Western blot shows the detection of FhkA by anti-FhkA at ~70 kDa as well as the absence of FhkA detection by the preimmune serum. (B) CBP4a possesses a putative FHA domain and putative NLS as well as four EF-hand Ca2+-binding motifs. The antigen site is shown for both FhkA and CBP4a.Back to article page