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Table 3 Deregulated centrosome genes

From: Differential expression of centrosome regulators in Her2+ breast cancer cells versus non-tumorigenic MCF10A cells

Gene symbol Gene name HCC1954/MCF10A
PLK2 polo-like kinase 2 5.82
SGOL1 shugoshin-like 1 (S. pombe) 4.24
CETN2 centrin, EF-hand protein, 2 4.12
AURKA aurora kinase A 4.01
BRCA1 breast cancer 1, early onset 3.77
CDK1 cyclin-dependent kinase 1 3.50
SON SON DNA binding protein 3.09
NEK2 NIMA (never in mitosis gene a)-related kinase 2 2.89
RANBP1 RAN binding protein 1 2.82
CEP76 centrosomal protein 76 kDa 2.46
GADD45A growth arrest and DNA-damage-inducible, alpha 2.40
TMEM67 transmembrane protein 67 2.40
TBCCD1 TBCC domain containing 1 2.36
SASS6 spindle assembly 6 homolog (C. elegans) 2.33
UXT ubiquitously-expressed, prefoldin-like chaperone 2.27
XPO1 exportin 1 (CRM1 homolog, yeast) 2.13
HAUS2 HAUS augmin-like complex, subunit 2 2.13
CEP192 centrosomal protein 192 kDa 2.03
HAUS7 HAUS augmin-like complex, subunit 7 2.03
SPICE1 spindle and centriole associated protein 1 2.01
CTNNB1 catenin (cadherin-associated protein), beta 1, 88 kDa 1.88
HAUS5 HAUS augmin-like complex, subunit 5 1.65
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45 kDa) 1.50
NDEL1 nudE nuclear distribution E homolog (A. nidulans)-like 1 −1.50
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10 −1.76
PKD2 polycystic kidney disease 2 (autosomal dominant) −1.80
PCM1 pericentriolar material 1 −1.82
CEP250 centrosomal protein 250 kDa −1.89
PLXNA2 plexin A2 −3.92
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A −6.99