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Table 4 Differential expression of selected cell cycle and centrosome genes

From: Differential expression of centrosome regulators in Her2+ breast cancer cells versus non-tumorigenic MCF10A cells

Accession number Genes down regulated in breast cancer cells Metacore fold change Fold changes, real-time PCR
    HCC1954 JIMT-1
[GenBank: NM_012395] CDK14 14.26 0.53 ± 0.48 1.19 ± 0.23
[GenBank:NM_014865.3] C-Nap1 1.89 0.90 ± 0.18 3.13 ± 0.27
[GenBank:NM_002392] MDM2 3.18 0.04 ± 0.01 0.28 ± 0.13
[GenBank:NM_025179] Plexin A2 3.92 0.37 ± 0.07 0.04 ± 0.01
[GenBank:NM_020796] Semaphorin 6A 6.99 0.01 ± 0.01 0.04 ± 0.01
[GenBank:NM_003012] SFRP1 38.04 0.00 ± 0.00 1.96 ± 0.07
  Genes up regulated in breast cancer cells    
[GenBank:NM_003318] TTK 4.62 2.10 ± 1.11 N/A
[GenBank:NM_198433] Aurora-A kinase 4.01 5.14 ± 0.91 3.2 ± 0.46
[GenBank:NM_001786] CDK1 3.5 1.06 ± 0.37 2.85 ± 0.65
[GenBank:NM_032142] CEP192 2.03 2.03 ± 0.81 4.36 ± 0.55
[GenBank:NM_004344] Centrin-2 4.12 2.42 ± 0.30 4.77 ± 1.27
[GenBank:NM_016095] GINS2 11.49 4.76 ± 1.59 1.41 ± 0.04
[GenBank:NM_004850] ROCK2 <1.5 1.46 ± 0.61 4.41 ± 0.70
[GenBank:NM_194292] SASS6 2.33 1.33 ± 0.36 2.13 ± 0.41
[GenBank:NM_144718] SPICE1 2.01 2.50 ± 0.87 2.45 ± 1.11
[GenBank:NM_001012410] SGOL1 4.24 1.49 ± 0.46 3.88 ± 0.26