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Figure 3 | Cell Division

Figure 3

From: Differential distribution of HP1 proteins after trichostatin a treatment influences chromosomal stability in HCT116 and WI-38 cells

Figure 3

Centromeric localization of histone marks, HP1α, and HP1β in HCT116 cells under basal conditions and after TSA treatment. (A) HCT116 chromatin localization by fluorescent microscopy of CENP-A with H3K9me3 (lane 1) or HP1α (lane 2), H3K9me3 and HP1α (lane 3), ACA and HP1β (lane 4), and HP1β and Mis12 (lane 5). (B) Centromeric localization of H3K9me3 and CENP-A (lane 1), CENP-A and HP1α (lane 2), ACA and HP1β (lane 3) and Mis12 co-localization with HP1β (lane 4). The DNA is marked with DAPI; the images show the most common distribution of the proteins after the analysis of 100 cells (%); the boxes represent a magnification of the immunofluorescent results; M, mitotic cell.

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