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Table 1 Analysis of total chromosome number in each cell after 24 and 48 h of trichostatin A (TSA) treatment

From: Differential distribution of HP1 proteins after trichostatin a treatment influences chromosomal stability in HCT116 and WI-38 cells

 

WI-38

HCT116

 

Control

24 h*

48 h*,**

Control

24 h

48 h**

Mode

42 (87.5%)

21(42%)

28 (54.9%)

49 (96.08%)

25 (54.9%)*

40 (78.43%)

Loss

6 (12.5%)

8 (16%)

11 (21.56%)

2 (3.92%)

14 (27.5%)*

7 (13.73%)

Gain

0

5 (10%)

2 (3.92%)

0

10 (19.6%)*

4 (7.84%)

4n

0

16 (32%)

10 (19.6%)

0

2 (3.9%)

0

Total

48

50

51

51

51

51

  1. Loss was considered below 2n, and gain was considered above 2n.
  2. *Levene’s test p < 0.001; treatment versus control.
  3. **Levene’s test p < 0.05; 24-h treatment versus 48-h treatment.