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Table 1 Analysis of total chromosome number in each cell after 24 and 48 h of trichostatin A (TSA) treatment

From: Differential distribution of HP1 proteins after trichostatin a treatment influences chromosomal stability in HCT116 and WI-38 cells

  WI-38 HCT116
  Control 24 h* 48 h*,** Control 24 h 48 h**
Mode 42 (87.5%) 21(42%) 28 (54.9%) 49 (96.08%) 25 (54.9%)* 40 (78.43%)
Loss 6 (12.5%) 8 (16%) 11 (21.56%) 2 (3.92%) 14 (27.5%)* 7 (13.73%)
Gain 0 5 (10%) 2 (3.92%) 0 10 (19.6%)* 4 (7.84%)
4n 0 16 (32%) 10 (19.6%) 0 2 (3.9%) 0
Total 48 50 51 51 51 51
  1. Loss was considered below 2n, and gain was considered above 2n.
  2. *Levene’s test p < 0.001; treatment versus control.
  3. **Levene’s test p < 0.05; 24-h treatment versus 48-h treatment.