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Fig. 4 | Cell Division

Fig. 4

From: Sumo and the cellular stress response

Fig. 4

Sumo and the ER stress response. Unfolded proteins trigger the ER stress response, inducing processing of XBP mRNA by Ire1, ultimately yielding active XBP1s. Sumoylation of XBP1s and the physical interaction with Ubc9 inhibit its transcriptional activity

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