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Table 1 Cul5-containing ubiquitin ligases and the corresponding substrates

From: The role of cullin 5-containing ubiquitin ligases

Cul5-type ubiquitin ligases Substrates References
SOCS1 JAK2 [63]
Vav [61]
IRS1 and IRS2 [66]
GM-CSF receptor βc subunit [60]
Cdh1 [65]
p65 [67]
Mal [64]
HPV E7 [62]
SOCS6 Cas [69]
SOCS7 Dab1 [86]
SPSB1, 2, and 4 iNOS [93, 94, 98, 99]
SPSB1 TGF-β type II receptor [102]
ASB2 Filamin A and B [107110]
Jak3 [112, 113]
ASB3 TNF-R2 [115]
ASB4 IRS4 [118]
ID2 [124]
ASB6 APS [125]
ASB9 CKB [130, 131]
uMtCK [132]
ASB11 DeltaA (in Danio rerio) [139, 140]
Ribophorin 1 [104]
WSB1 HIPK2 [144]
D2 [160]
pVHL [165]
RhoGDI2 [166]
Rab40 Rap2 GTPase [167]
Elongin A Rpb1 [170]
Vif (human immunodeficiency virus) APOBEC3F [188]
APOBEC3G [186]
BZLF1 (Epstein–Barr virus) p53 [224, 225]
E1B55K (adenovirus) p53 [235, 236, 239]
Mre11 [227]
DNA ligase IV [241, 242]
integrin α3 [243]
Rep52 and capsid proteins [244, 245]
LANA (Kaposi’s sarcoma–associated herpesvirus) pVHL and p53 [254]