Fig. 4From: The CSL proteins, versatile transcription factors and context dependent corepressors of the notch signaling pathwayCIR-CSL interaction: CBF-1 interacting region for CIR is located at the BTD of CBF-1 (a CSL protein) that matches the domain used by the RAM domain of NICD. This interaction suggests a competition for the transcription factor, regulating in a negative fashion genes regulated by NSP in a specific cell contextBack to article page