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Table 1 Frequency of compound mutant mice

From: Multiple molecular interactions redundantly contribute to RB-mediated cell cycle control

E2f1 /; Rb1 G/+ ; Cdkn1b +/ × E2f1 /; Rb1 G/+ ; Cdkn1b +/

 

Genotype

P14

E2f1 / ; Rb1 +/+ ; Cdkn1b +/+

8 (13)

E2f1 / ; Rb1 +/+ ; Cdkn1b +/

29 (26)

E2f1 / ; Rb1 +/+ ; Cdkn1b /

12 (13)

E2f1 / ; Rb1 G/+ ; Cdkn1b +/+

29 (26)

E2f1 / ; Rb1 G/+ ; Cdkn1b +/

64 (52)

E2f1 / ; Rb1 G/+ ; Cdkn1b /

9a (26)

E2f1 / ; Rb1 G/G ; Cdkn1b +/+

12 (13)

E2f1 / ; Rb1 G/G ; Cdkn1b +/

35 (26)

E2f1 / ; Rb1 G/G ; Cdkn1b /

10 (13)

Total

208

  1. The indicated genotypes of mice were crossed and all resulting progeny were genotyped. The number of live animals obtained at 2 weeks of age is indicated for each genotype and the expected number based on Mendelian inheritance is indicated in brackets
  2. a Indicates significance as determined by Chi squared test