Protein name | Effect on cell cycle | Phase separation | |
---|---|---|---|
Nucleolus | |||
 FIBL | Knockdown reduces cell growth [57] | [12] | |
 NPM-1a | Role in tumorigenesis [58] | [12] | |
Stress granule | |||
 eIF4G2 | Knockdown induces apoptosis and impairs proliferation [59] | [9] | |
 FUSa | Knockdown impairs cell proliferation [60] | ||
 EWSa | Knockdown induces apoptosis and impairs proliferation [61] | [2] | |
 hnRNPA1 | Knockdown induces cell cycle arrest [62] | ||
 TDP-43 | Overexpression induces cell cycle arrest [63] | [64] | |
 TIA-1 | Knockdown promotes cell proliferation [65] | [9] | |
Centrosome | |||
 PCM-1 | Involved in cell cycle progression [66] | [67] | |
Purinosome | |||
 PPAT | Regulates growth rate via de novo purine biosynthesis [68] | [69] | |
Nuclear pore | |||
 Nup98a | Regulates expression cell cycle genes [70] | [71] | |
T-cell receptor | |||
 LAT | Regulates T-cell activation and proliferation [72] | [40] |