Fig. 9From: FGF-induced LHX9 regulates the progression and metastasis of osteosarcoma via FRS2/TGF-β/β-catenin pathwayLHX9 regulates OS development through binding withβ-catenin and inhibiting its degradation. a U2OS cells or Saos-2 cells were transfected with Myc-tagged beta-catenin, Flag-tagged LHX9 or both, then they were cultured for 48 h. The interaction between beta-catenin and LHX9 was assessed by Co-IP experiment. β-actin was used as the loading controlBack to article page