Fig. 3From: IGFBP5 increases cell invasion and inhibits cell proliferation by EMT and Akt signaling pathway in Glioblastoma multiforme cellsInhibit IGFBP5 repressed GBM cell invasion. Matrigel cell invasion assay showed that knockdown of IGFBP5 inhibited the invasion ability of U251 (a) and G1 (c) cells. Scale bar = 50 μm. b, d Western blot confirmed the reduced proteins’ levels of N-cadherin and Vimentin in siBP5 cells (U251 and G1) relative to control. *P < 0.05, **P < 0.01, ***P < 0.001 and ****P < 0.0001Back to article page