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Fig. 5 | Cell Division

Fig. 5

From: The G2-to-M transition from a phosphatase perspective: a new vision of the meiotic division

Fig. 5

Generating a Cdk1 starter to launch the Cdk1 feedback loop. In response to progesterone, Cyclin B1 accumulates, binds monomeric Cdk1 and forms Cdk1-Cyclin B1 complexes that escape Myt1 inhibition and cause inactivating phosphorylation of Myt1. Hence, these few active complexes serve as a switch to initiate the MPF activation loop from the stockpiled Cdk1-Cyclin B2 complexes

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