Fig. 4
From: Chromosomal aberration arises during somatic reprogramming to pluripotent stem cells
Occurrence of chromosomal aberrations during clonal reprogramming process. a The schematic protocols depict two treatments for HDF clones. b Quantification of EDU+ cells in GFP mRNA transfection and KMOS mRNAs transfection. c List of the abnormal karyotypes detected in human dermal fibroblast (HDF) clonal reprogramming. d Representative abnormal karyotype detected in HDF clonal reprogramming. Red arrowheads indicate an abnormal chromosome X and a lost chromosome 22. e List of the abnormal karyotypes detected in human hair follicle cell (HHFC) clonal reprogramming. Statistical analyses are presented as Mean ± SD, n = 3. *P < 0.05, **P < 0.01