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Table 5 The association of TBK1 score with the clinical variables in the Moffitt Cancer Center’s TNBC cohort

From: Ethnic and racial-specific differences in levels of centrosome-associated mitotic kinases, proliferative and epithelial-to-mesenchymal markers in breast cancers

 

TBK1 expression = 0

TBK1 expression > 0

P-value

N = 63

N = 66

Race

  

0.182

 Black

22 (59.5%)

15 (40.5%)

 

 White

41 (44.6%)

51 (55.4%)

 

Mean TTK score

  

0.213

 TTK expression = 0

20 (40.8%)

29 (59.2%)

 

 TTK expression > 0

43 (53.8%)

37 (46.2%)

 

Mean Vimentin score

  

0.684

 Vimentin expression = 0

20 (46.5%)

23 (53.5%)

 

 Vimentin expression > 0

29 (52.7%)

26 (47.3%)

 

Mean E-cadherin score:

  

1.000

 E-cadherin expression = 0

33 (52.4%)

30 (47.6%)

 

 E-cadherin expression > 0

22 (52.4%)

20 (47.6%)

 

Mean Ki67 score

  

0.091

 Ki67 expression = 0

36 (56.2%)

28 (43.8%)

 

 Ki67 expression > 0

25 (39.7%)

38 (60.3%)

 
  1. Allred score of TBK1 was treated as the categorical variable as non-expression (Allred score = 0, n = 63) and expression (Allred score > 0, n = 66). The clinical variables include race, hormone receptors, and mean score of TTK, E-cadherin, and Ki67 biomarkers. P-values were derived from Chi-squared tests
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Cell Division

ISSN: 1747-1028

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