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Fig. 6 | Cell Division

Fig. 6

From: Sustained Shugoshin 1 downregulation reduces tumor growth and metastasis in a mouse xenograft tumor model of triple-negative breast cancer

Fig. 6

SGO1 modulates EMT mRNA expression. Graphs show the average mRNA fold changes relative to GAPDH (obtained by quantitative real-time PCR) of SGO1 (a), EMT transcription factors (Snail and Slug) (b), and MMP (MMP2, MMP3, and MMP9) (c) mRNA expression in shRNA Control or shRNA SGO1 MDA-MB-231 cells. Experiments were done as biological triplicates. Error bars represent mean ± SEM. *p < 0.05, **p < 0.01, and ***p < 0.001 were considered statistically significant. N.S. stands for not significant. A Student t-test (unpaired, two-tailed) was used to compare differences between groups

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Cell Division

ISSN: 1747-1028

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