Fig. 7

SGO1 downregulation significantly decreases cell proliferation and viability. Graph showing the average cell proliferation and viability for MDA-MB-231 cells treated with shRNA SGO1 compared to shRNA Control (a). Error bars represent mean ± SEM. *p < 0.05, **p < 0.01, and ***p < 0.001 were considered statistically significant. A Student t-test (unpaired, two-tailed) was used to compare differences between groups. Cell sorting analysis showing the percentage of viable, necrotic, early apoptotic, or late apoptotic shRNA Control (b) or shRNA SGO1 (c) MDA-MB-231 cells. Graph showing the average of three experiments (d). Error bars represent mean ± SEM. *p < 0.05, **p < 0.01, and ***p < 0.001 were considered statistically significant. N.S. stands for not significant. A Student t-test (unpaired, two-tailed) was used to compare differences between groups