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  1. Commentary

    Systematic epistatic mapping of cellular processes

    Genetic screens have identified many novel components of various biological processes, such as components required for cell cycle and cell division. While forward genetic screens typically generate unstructure...

    Maximilian Billmann and Michael Boutros

    Cell Division 2017 12:2

    Published on: 6 January 2017

  2. Review

    The CSL proteins, versatile transcription factors and context dependent corepressors of the notch signaling pathway

    The Notch signaling pathway is a reiteratively used cell to cell communication pathway that triggers pleiotropic effects. The correct regulation of the pathway permits the efficient regulation of genes involve...

    Humberto Contreras-Cornejo, Germán Saucedo-Correa, Javier Oviedo-Boyso, Juan José Valdez-Alarcón, Víctor Manuel Baizabal-Aguirre, Marcos Cajero-Juárez and Alejandro Bravo-Patiño

    Cell Division 2016 11:12

    Published on: 27 September 2016

  3. Research

    Interferon gamma-induced apoptosis of head and neck squamous cell carcinoma is connected to indoleamine-2,3-dioxygenase via mitochondrial and ER stress-associated pathways

    Tumor response to immunotherapy is the consequence of a concerted crosstalk between cytokines and effector cells. Interferon gamma (IFNγ) is one of the common cytokines coordinating tumor immune response and t...

    Siraj M. El Jamal, Erin B. Taylor, Zakaria Y. Abd Elmageed, Abdulhadi A. Alamodi, Denis Selimovic, Abdulaziz Alkhateeb, Matthias Hannig, Sofie Y. Hassan, Simeon Santourlidis, Paul L. Friedlander, Youssef Haikel, Srinivasan Vijaykumar, Emad Kandil and Mohamed Hassan

    Cell Division 2016 11:11

    Published on: 2 August 2016

  4. Review

    Cullin-RING ligases in regulation of autophagy

    Cullin-RING ligases (CRLs), the largest E3 ubiquitin ligase family, promote ubiquitination and degradation of various cellular key regulators involved in a broad array of physiological and pathological process...

    Danrui Cui, Xiufang Xiong and Yongchao Zhao

    Cell Division 2016 11:8

    Published on: 10 June 2016

  5. Research

    Mitochondria-cytoskeleton associations in mammalian cytokinesis

    The role of the cytoskeleton in regulating mitochondrial distribution in dividing mammalian cells is poorly understood. We previously demonstrated that mitochondria are transported to the cleavage furrow durin...

    E. J. Lawrence, E. Boucher and C. A. Mandato

    Cell Division 2016 11:3

    Published on: 18 March 2016

  6. Review

    The role of cullin 5-containing ubiquitin ligases

    The suppressor of cytokine signaling (SOCS) box consists of the BC box and the cullin 5 (Cul5) box, which interact with Elongin BC and Cul5, respectively. SOCS box-containing proteins have ubiquitin ligase act...

    Fumihiko Okumura, Akiko Joo-Okumura, Kunio Nakatsukasa and Takumi Kamura

    Cell Division 2016 11:1

    Published on: 9 March 2016

  7. Review

    Curcumin and tumor immune-editing: resurrecting the immune system

    Curcumin has long been known to posses medicinal properties and recent scientific studies have shown its efficacy in treating cancer. Curcumin is now considered to be a promising anti-cancer agent and studies ...

    Sayantan Bose, Abir Kumar Panda, Shravanti Mukherjee and Gaurisankar Sa

    Cell Division 2015 10:6

    Published on: 12 October 2015

  8. Review

    Sumo and the cellular stress response

    The ubiquitin family member Sumo has important functions in many cellular processes including DNA repair, transcription and cell division. Numerous studies have shown that Sumo is essential for maintaining cel...

    Jorrit M. Enserink

    Cell Division 2015 10:4

    Published on: 20 June 2015

  9. Short report

    Cyclin E2 is the predominant E-cyclin associated with NPAT in breast cancer cells

    The cyclin E oncogene activates CDK2 to drive cells from G1 to S phase of the cell cycle to commence DNA replication. It coordinates essential cellular functions with the cell cycle including histone biogenesis, ...

    Samuel Rogers, Brian S Gloss, Christine S Lee, Claudio Marcelo Sergio, Marcel E Dinger, Elizabeth A Musgrove, Andrew Burgess and Catherine Elizabeth Caldon

    Cell Division 2015 10:1

    Published on: 19 February 2015

  10. Research

    Differential distribution of HP1 proteins after trichostatin a treatment influences chromosomal stability in HCT116 and WI-38 cells

    Heterochromatin protein 1 (HP1) is important in the establishment, propagation, and maintenance of constitutive heterochromatin, especially at the pericentromeric region. HP1 might participate in recruiting an...

    Rodrigo González-Barrios, Ernesto Soto-Reyes, Ricardo Quiroz-Baez, Eunice Fabián-Morales, José Díaz-Chávez, Victor del Castillo, Julia Mendoza, Alejandro López-Saavedra, Clementina Castro and Luis A Herrera

    Cell Division 2014 9:6

    Published on: 30 December 2014

  11. Commentary

    Polar electrostatic forces drive poleward chromosome motions

    Recent experiments revealing nanoscale electrostatic force generation at kinetochores for chromosome motions have prompted models for interactions between positively charged molecules in kinetochores and negat...

    Lucian John Gagliardi and Daniel H Shain

    Cell Division 2014 9:5

    Published on: 30 December 2014

  12. Research

    The subunits of the S-phase checkpoint complex Mrc1/Tof1/Csm3: dynamics and interdependence

    The S-phase checkpoint aims to prevent cells from generation of extensive single-stranded DNA that predisposes to genome instability. The S. cerevisiae complex Tof1/Csm3/Mrc1 acts to restrain the replicative MCM ...

    Sonya Dimitrova Uzunova, Alexander Stefanov Zarkov, Anna Marianova Ivanova, Stoyno Stefanov Stoynov and Marina Nedelcheva Nedelcheva-Veleva

    Cell Division 2014 9:4

    Published on: 31 October 2014

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