Table 1 Growth inhibition effect of various constituents of D. versipellis on different cells

PC3

Bcap-37

BGC-823

NIT3T3

β-sitosterol

14.7 ± 8.5

10.9 ± 10.4

19.5 ± 9.3

1.7 ± 9.3

4'-demethylpodophyllotoxin

60.5 ± 5.2**

56.7 ± 9.1**

56.9 ± 12.4

60.1 ± 6.1**

Kaempferol

43.9 ± 11.9**

53.2 ± 10.9**

53.4 ± 14.9

39.2 ± 8.2**

picropodophyllotoxin-4-O-glucoside

9.0 ± 9.9

7.4 ± 9.3

24.6 ± 11.3**

6.4 ± 8.8

kaempferol-3-O-β-D-glucopyranoside

23.0 ± 6.4**

29.9 ± 10.8**

13.2 ± 8.7

23.0 ± 7.9**

4'-demethylpodophyllotoxin-4-O-glucoside

19.8 ± 7.1**

21.9 ± 6.5**

14.5 ± 8.0

6.5 ± 7.7

quercetin-3-O-β-D-glucopyranoside

11.6 ± 9.1

15.2 ± 10.1

40.7 ± 11.9**

5.1 ± 9.9

icropodophyllotoxin-4-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranoside.

10.2 ± 8.1

23.9 ± 10.2

23.6 ± 10.7**

2.2 ± 8.8

Quercetin

29.8 ± 8.3

39.0 ± 13.3**

22.1 ± 4.3*

8.1 ± 5.0

Podophyllotoxone

52.0 ± 5.6**

42.1 ± 6.3**

47.9 ± 8.1

43.7 ± 6.2**

vanillic acid

29.2 ± 3.9**

30.3 ± 10.9**

28.5 ± 12.3

10.2 ± 5.0*

4'-demethyldeoxypodophyllotoxin

67.1 ± 3.4**

56.6 ± 12.3**

60.7 ± 9.8**

59.8 ± 3.5**

ADM

93.2 ± 1.6

90.6 ± 1.2**

98.3 ± 4.0**

97.5 ± 1.7**