Figure 8From: Smurf2 E3 ubiquitin ligase modulates proliferation and invasiveness of breast cancer cells in a CNKSR2 dependent manner Silencing of Smurf2 downregulates Ki-67 expression. Smurf2 knockdown significantly downregulated the expression of the proliferation marker Ki-67 in (A) MDA-MB-231 and (B) MCF-7 cells compared to control siRNA treated cells.Back to article page