SIRT4 is an independent prognostic factor in bladder cancer and inhibits bladder cancer growth by suppressing autophagy

Table 1 Correlation between SIRT4 levels and clinicopathologic variables in bladder urothelial carcinoma

Clinicopathologic parameters	SIRT4 levels			χ²	P value^a
Clinicopathologic parameters	All cases	Low	High	χ²	P value^a
Age (years)				0.01	0.92
≤ 60	14	6	8
> 60	45	20	25
Gender				2.78	0.14
Male	50	20	30
Female	9	1	8
Tumor size (cm)				6.0	0.02
≤ 5	37	10	27
> 5	22	13	9
Differentiation				0.21	0.65
I-II	20	6	14
III-IV	39	14	25
Stage (T)				5.4	0.02
T1-T2	33	6	27
T3-T4	26	12	14
Stage (N)				0.01	0.92
N0	37	13	24
N1-N2	22	8	14
AJCC stage				5.5	0.02
I-II	34	10	24
III-IV	25	15	10

ISSN: 1747-1028