Skip to main content
Fig. 5 | Cell Division

Fig. 5

From: The roles of METTL3 on autophagy and proliferation of vascular smooth muscle cells are mediated by mTOR rather than by CDK1

Fig. 5

CDK1 knockdown eliminated the pro-proliferative effect of METTL3 on VSMC. A–D The protein levels of METTL3, CDK1 and phosphorylated CDK1 (p-CDK1) were evaluated by using western blotting in HASMCs with METTL3 and CDK1 knockdown or not (A); (B-D) Quantitative results of blots in A (n = 4). E–G The expression levels of proliferation markers p-H3 and PCNA were measured in HASMCs with indicated treatments by using western blotting (E); F and G Quantitative results of indicated blots in E (n = 4). β-actin serves as loading control. *p < 0.05 versus lenti-shRNA + lenti-shRNA; #p < 0.05 versus lenti-shRNA + lenti-shMETTL3-1; &p < 0.05 versus lenti-shRNA + lenti-shMETTL3-2

Back to article page

Cell Division

ISSN: 1747-1028

Contact us