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Fig. 6 | Cell Division

Fig. 6

From: The roles of METTL3 on autophagy and proliferation of vascular smooth muscle cells are mediated by mTOR rather than by CDK1

Fig. 6

CDK1 involved in the regulation of autophagy but did not reverse the function of METTL3 on autophagy in VSMC. A–C Representative western blots and quantification results of phosphorylated ULK1 (p-ULK1) and p-mTOR (n = 4). D–G The expression levels of ATG5, ATG7 and LC3 in HASMCs with the indicated treatments (D); E–G Quantitative results of indicated blots in D (n = 4). β-actin serves as loading control. *p < 0.05 versus lenti-shRNA + lenti-shRNA; #p < 0.05 versus lenti-shRNA + lenti-shMETTL3-1; &p < 0.05 versus lenti-shRNA + lenti-shMETTL3-2

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