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Fig. 1 | Cell Division

Fig. 1

From: Preeclampsia-associated lncRNA FEZF1-AS1 regulates cell proliferation and apoptosis in placental trophoblast cells through the ELAVL1/NOC2L axis

Fig. 1

FEZF1-AS1 promotes proliferation and inhibits apoptosis of trophoblast cells. In order to investigate the disparity in the expression of FEZF1-AS1 in PE and normal placental tissues, the following experiment was conducted. A The expression of FEZF1-AS1 was detected by qPCR, n = 30, **p < 0.01. FEZF1-AS1 was knocked down or overexpressed in HTR-8/SVneo cell lines, and they were grouped as follows: si-NC, si-FEZF1-AS1, oe-NC, and oe-FEZF1-AS1. B The silencing and overexpression efficiency of FEZF1-AS1 was evaluated using qPCR. C The CCK-8 assay was used to measure cell viability. D The EdU assay was used to detect cell proliferation. E Apoptosis was detected using the TUNEL assay. F The protein expressions of Bcl-2, Bax, and cleaved Caspase3 were detected by western blot. n = 3, *p < 0.05, **p < 0.01, ***p < 0.001

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Cell Division

ISSN: 1747-1028

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