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Fig. 2 | Cell Division

Fig. 2

From: Preeclampsia-associated lncRNA FEZF1-AS1 regulates cell proliferation and apoptosis in placental trophoblast cells through the ELAVL1/NOC2L axis

Fig. 2

NOC2L promotes the proliferation and inhibits the apoptosis of trophoblast cells. For investigating the differential expression of NOC2L in PE and normal placental tissues, the following experiment was conducted. A The expression of NOC2L was detected using qPCR, n = 30, **p < 0.01. NOC2L was knocked down or overexpressed in HTR-8/SVneo cell lines, which were grouped as follows: si-NC, si-NOC2L, oe-NC, and oe-NOC2L. B The silencing and overexpression efficiency of NOC2L was evaluated using qPCR. C The silencing and overexpression efficiency of NOC2L was verified using western blot. D The CCK-8 assay was used to measure cell viability. E The EdU assay was used to detect cell proliferation. F Apoptosis was detected using the TUNEL assay. G The protein expressions of Bcl-2, Bax, and cleaved caspase-3 were detected by western blot. n = 3, *p < 0.05, **p < 0.01, ***p < 0.001

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Cell Division

ISSN: 1747-1028

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