Skip to main content
Fig. 3 | Cell Division

Fig. 3

From: Preeclampsia-associated lncRNA FEZF1-AS1 regulates cell proliferation and apoptosis in placental trophoblast cells through the ELAVL1/NOC2L axis

Fig. 3

FEZF1-AS1 and NOC2L bind to ELAVL1. A ENCORI predicted that FEZF1-AS1 and NOC2L have binding sites with ELAVL1. In order to verify the interaction between FEZF1-AS1 and NOC2L with ELAVL1, the following experiment was conducted. B RNA pull-down verified the binding relationship between ELAVL1 and FEZF1-AS1, as well as ELAVL1 and NOC2L. NOC2L was knocked down or overexpressed in HTR-8/SVneo cell lines, which were grouped as follows: si-NC, si-NOC2L, oe-NC, and oe-NOC2L. C The RIP assay was used to detect the effect of NOC2L on the interaction between ELAVL1 and NOC2L. FEZF1-AS1 was knocked down or overexpressed in HTR-8/SVneo cell lines, and they were grouped as follows: si-NC, si-FEZF1-AS1, oe-NC, oe-FEZF1-AS1. D The RIP assay was used to detect the effect of FEZF1-AS1 on the interaction between ELAVL1 and NOC2L. n = 3, **p < 0.01, ***p < 0.001

Back to article page

Cell Division

ISSN: 1747-1028

Contact us