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Fig. 5 | Cell Division

Fig. 5

From: Preeclampsia-associated lncRNA FEZF1-AS1 regulates cell proliferation and apoptosis in placental trophoblast cells through the ELAVL1/NOC2L axis

Fig. 5

The FEZF1-AS1/ELAVL1/NOC2L signaling axis influences the proliferation and apoptosis of trophoblast cells. To investigate the regulation of trophoblast cell proliferation and apoptosis by the FEZF1-AS1/ELAVL1/NOC2L signaling axis, we conducted a recovery experiment. The groups were categorized as follows: oe-NC, oe-FEZF1-AS1, oe-FEZF1-AS1 + si-ELAVL1, and oe-FEZF1-AS1 + si-NOC2L. A The CCK-8 assay was used to measure cell viability. B The EdU assay was used to detect cell proliferation. C Apoptosis was detected using the TUNEL assay. D The protein expressions of Bcl-2, Bax, and cleaved caspase-3 were detected by western blot. n = 3, *p < 0.05, **p < 0.01, ***p < 0.001

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