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Fig. 4 | Cell Division

Fig. 4

From: Angelica acutiloba Kitagawa flower induces A549 cell pyroptosis via the NF-κB/NLRP3 pathway for anti-lung cancer effects

Fig. 4

KAE- and PLA-mediated pyroptosis and upregulation of inflammatory factors in A549 cells. A Morphological effects of KAE and PLA on A549 cells: note cell swelling, formation of pore vesicles on the plasma membrane, and pyroptosis that was particularly obvious under 100 μM PLA. B and C Staining of A549 cells separately using Hoechst 33,342/PI (B) and Annexin V-FITC/PI (C) to examine the effects of KAE and PLA treatment on A549 pyroptosis. D ELISA of IL-1β and IL-18 expression levels in A549 cells. *P < 0.05, **P < 0.01, ***P < 0.001 vs. control group

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