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Fig. 6 | Cell Division

Fig. 6

From: Angelica acutiloba Kitagawa flower induces A549 cell pyroptosis via the NF-κB/NLRP3 pathway for anti-lung cancer effects

Fig. 6

KAE and PLA exert their effects by targeting the NLRP3 protein and activating the NLRP3 inflammasome. A CETSA was employed to investigate the interaction between KAE, PLA, and NLRP3. B Immunoprecipitation studies further demonstrated that KAE and PLA not only up-regulated the expression of NLRP3 but also enhanced its binding to ASC. ***P < 0.001 vs. control group

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Cell Division

ISSN: 1747-1028

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