Fig. 7From: Angelica acutiloba Kitagawa flower induces A549 cell pyroptosis via the NF-κB/NLRP3 pathway for anti-lung cancer effectsMechanism of NLRP3 inflammasome activation and activities of associated proteins. KAE and PLA induce the NLRP3 inflammasome to assemble by increasing ROS levels, further upregulating NF-κB, NLRP3, and ASC protein expression, and thereby activating caspase-1 to shear its target protein GSDMD and induce pyroptosisBack to article page