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Fig. 3 | Cell Division

Fig. 3

From: Exosome-derived lncRNA A1BG-AS1 attenuates the progression of prostate cancer depending on ZC3H13-mediated m6A modification

Fig. 3

Exosome-derived A1BG-AS1 suppresses PCa cell malignancy. A The exosome markers (CD63 and CD9) were uncovered by western blot analysis. B The levels of A1BG-AS1 in cellular and Exosomal of 22RV1 as well as C4-2B cells were uncovered through qRT-PCR. **P < 0.001 vs. Cellular. C The levels of A1BG-AS1 in 22RV1 as well as C4-2B cells in Exo-vector and Exo-A1BG-AS1 groups were uncovered through qRT-PCR. D Cell viability of 22RV1 as well as C4-2B cells in Exo-vector and Exo-A1BG-AS1 groups were uncovered through CCK-8 assay. E Cell proliferation of 22RV1 as well as C4-2B cells in Exo-vector and Exo-A1BG-AS1 groups were uncovered through colony formation assay. F Cell migration of 22RV1 as well as C4-2B cells in Exo-vector and Exo-A1BG-AS1 groups were uncovered through Transwell assay. G Cell invasion of 22RV1 as well as C4-2B cells in Exo-vector and Exo-A1BG-AS1 groups were uncovered through Transwell assay. C–G Exo-vector group, the exosomes of 22RV1 cells and C4-2B cells in Empty vector group were co-cultured with 22RV1 cells and C4-2B cells, respectively. Exo-A1BG-AS1 group, the exosomes of 22RV1 cells and C4-2B cells in pc3.1-A1BG-AS1 group were co-cultured with 22RV1 cells and C4-2B cells, respectively. **P < 0.001 vs. Exo-vector

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