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Fig. 4 | Cell Division

Fig. 4

From: Exosome-derived lncRNA A1BG-AS1 attenuates the progression of prostate cancer depending on ZC3H13-mediated m6A modification

Fig. 4

ZC3H13 mediates stable expression of A1BG-AS1 with m6A modification in PCa. A The m6A site of A1BG-AS1 was shown by RMBase v2.0. B The level of ZC3H13 in PCa samples were revealed by TCGA. C The correlation among A1BG-AS1 and ZC3H13 expression were revealed by TCGA. D The level of ZC3H13 in PCa samples normal tissues were revealed by qRT-PCR. E The correlation among A1BG-AS1 and ZC3H13 expression were revealed by Pearson analysis. F The level of ZC3H13 protein in 22RV1 as well as C4-2B cells treated with pc3.1-ZC3H13 or Empty vector were uncovered through western blotting. G The level of m6A modification of A1BG-AS1 was measured through MeRIP assay in 22RV1 as well as C4-2B cells treated with pc3.1-ZC3H13 or Empty vector. H The level of A1BG-AS1 in 22RV1 as well as C4-2B cells transfected with pc3.1-ZC3H13 or Empty vector after treated with actinomycin D at the indicated time points were detected by qRT-PCR. **P < 0.001 vs. Empty vector

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