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Fig. 1 | Cell Division

Fig. 1

From: Zinc finger protein 468 up-regulation of TFAM contributes to the malignant growth and cisplatin resistance of breast cancer cells

Fig. 1

BC samples and cells have higher expression of ZNF468. A The transcript level of ZNF468 was analyzed in pan-cancer based on the database from TCGA. Most of the cancers showed higher expression ZNF468. n.s, no significance. *p < 0.05. B Analysis of ZNF468 transcript was conducted in cancer (n = 1085) and normal tissues (n = 291) derived from BC patients. p < 0.05. C Overall survival was analyzed on BC patients who were divided into ZNF468 high expression (n = 212) and low expression (n = 213) group. p = 0.022. D Cancer (n = 12) and normal tissues (n = 12) of BC patients were collected for immunoblotting analysis of ZNF468. Quantification of ZNF468 protein abundance was adjusted to GAPDH. p < 0.01. E The expression of ZNF468 was determined by immunoblotting assay in breast immortalized cells MCF-10A and in BC cells MCF-7, MDA-MB-468 and MDA-MB-231. For immunoblotting assays, the blots were cut prior to hybridisation with antibodies

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