Table 1 Substrates of APC^Cdh1.

Cdc20

anaphase onset

[16, 17]

Securin

anaphase onset

[18, 19]

Sgo1

anaphase onset

[20]

Rcs1

anaphase onset

[21]

XKid

spindle assembly

[22, 23]

Tpx2

spindle assembly

[24]

Ase1

spindle assembly

[25, 26]

Aurora A

mitotic exit

[27, 28]

Aurora B

mitotic exit

[29]

Plk1

mitotic exit

[30]

Anillin

mitotic exit

[31]

CKAP2

mitotic exit

[32]

Cyclin B1

mitotic exit

[33]

Cyclin A

mitotic exit

[34]

Cdc6

DNA synthesis

[35–37]

Geminin

DNA synthesis

[38, 39]

FoxM1

G1/G0 maintenance

[40, 41]

SnoN

Tgf-β signaling

[42, 43]

Ets2

Ras signaling

[77]

Id2

transcription

[86]