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  1. ‘Dormancy’, in the context of carcinogenesis, is a biological phenomenon of decreased cancer cell proliferation and metabolism. In view of their ability to remain quiescent, cancer cells are able to avoid cell...

    Authors: Tatiana G. Ruksha

    Citation: Cell Division 2019 14:11

    Content type: Review

    Published on:

  2. The authors note a correction to the article [1]. Figure 1d of the original article has an error. The pcDNA3/Ctrl and the pcDNA3-TAp73a/DMSO wells are duplicated. This article presents the corrected version of...

    Authors: Alicja Sznarkowska, Anna Kostecka, Anna Kawiak, Pilar Acedo, Mattia Lion, Alberto Inga and Joanna Zawacka‑Pankau

    Citation: Cell Division 2019 14:10

    Content type: Correction

    Published on:

    The original article was published in Cell Division 2018 13:10

  3. A previous screen of a human kinase and phosphatase shRNA library to select genes that mediate arsenite induction of spindle abnormalities resulted in the identification of phosphatidylinositol-5-phosphate 4-k...

    Authors: Tz-Chi Lin, Hsiao-Hui Kuo, Yi-Chen Wu, Tiffany S. Pan and Ling-Huei Yih

    Citation: Cell Division 2019 14:9

    Content type: Research

    Published on:

  4. Integrin-mediated adhesion is normally required for cytokinetic abscission, and failure in the process can generate potentially oncogenic tetraploid cells. Here, detachment-induced formation of oncogenic tetra...

    Authors: Deepesh Kumar Gupta, Siamak A. Kamranvar, Jian Du, Liangwen Liu and Staffan Johansson

    Citation: Cell Division 2019 14:8

    Content type: Research

    Published on:

  5. Nuclear pore complexes (NPCs) act as nano-turnstiles within nuclear membranes between the cytoplasm and nucleus of mammalian cells. NPC proteins, called nucleoporins (Nups), mediate trafficking of proteins and...

    Authors: Hartono, Masaharu Hazawa, Kee Siang Lim, Firli R. P. Dewi, Akiko Kobayashi and Richard W. Wong

    Citation: Cell Division 2019 14:7

    Content type: Short report

    Published on:

  6. To investigate the role of P16 (INK4a)-extracellular signal related kinase 1/2 (ERK1/2) signaling pathway in cisplatin (DDP) resistance induced by multidrug resistance protein 1 (MDR1), also known as P-glycopr...

    Authors: Yun Xiao, Mei-rong Liang, Cheng-cheng Liu, Ya-nan Wang, Yang Zeng, Jun Zhou, Hui-ting Zhu, Qin Wang, Yang Zou and Si-yuan Zeng

    Citation: Cell Division 2019 14:6

    Content type: Research

    Published on:

  7. Drugs such as taxanes, epothilones, and vinca alkaloids are widely used in the treatment of breast, ovarian, and lung cancers but come with major side effects such as neuropathy and loss of neutrophils and as ...

    Authors: Jianquan Li, Nanmao Dang, Nuria Martinez-Lopez, Paul A. Jowsey, Dong Huang, Robert N. Lightowlers, Fei Gao and Jun-Yong Huang

    Citation: Cell Division 2019 14:5

    Content type: Research

    Published on:

  8. Resveratrol and its natural stilbene-containing derivatives have been extensively investigated as potential chemotherapeutic agents. The synthetic manipulation of the stilbene scaffold has led to the generatio...

    Authors: Gianandrea Traversi, David Sasah Staid, Mario Fiore, Zulema Percario, Daniela Trisciuoglio, Roberto Antonioletti, Veronica Morea, Francesca Degrassi and Renata Cozzi

    Citation: Cell Division 2019 14:3

    Content type: Research

    Published on:

  9. The p27kip1 protein, mainly known as a negative regulator of cell proliferation, has also been involved in the control of other cellular processes, including the regulation of cytoskeleton dynamics. Notably, thes...

    Authors: Gian Luca Rampioni Vinciguerra, Francesca Citron, Ilenia Segatto, Barbara Belletti, Andrea Vecchione and Gustavo Baldassarre

    Citation: Cell Division 2019 14:2

    Content type: Commentary

    Published on:

  10. Mechanisms controlling DNA resection at sites of damage and affecting genome stability have been the subject of deep investigation, though their complexity is not yet fully understood. Specifically, the regula...

    Authors: Nagaraja Chappidi, Giuseppe De Gregorio and Stefano Ferrari

    Citation: Cell Division 2019 14:1

    Content type: Short Report

    Published on:

  11. The p73 protein is a tumor suppressor that shares structural and functional similarity with p53. p73 is expressed in two major isoforms; the TA isoform that interacts with p53 pathway, thus acting as tumor sup...

    Authors: Alicja Sznarkowska, Anna Kostecka, Anna Kawiak, Pilar Acedo, Mattia Lion, Alberto Inga and Joanna Zawacka-Pankau

    Citation: Cell Division 2018 13:10

    Content type: Research

    Published on:

    The Correction to this article has been published in Cell Division 2019 14:10

  12. During oocyte meiosis, the cytoskeleton dynamics, especially spindle organization, are critical for chromosome congression and segregation. However, the roles of the kinesin superfamily in this process are sti...

    Authors: Feng Tang, Meng-Hao Pan, Xiang Wan, Yujie Lu, Yu Zhang and Shao-Chen Sun

    Citation: Cell Division 2018 13:9

    Content type: Research

    Published on:

  13. Membrane-associated progesterone receptors are restricted to the endoplasmic reticulum and are shown to regulate the activity of cytochrome P450 enzymes which are involved in steroidogenesis or drug detoxifica...

    Authors: Ramona Jühlen, Dana Landgraf, Angela Huebner and Katrin Koehler

    Citation: Cell Division 2018 13:8

    Content type: Research

    Published on:

  14. Aurora kinases are serine/threonine kinases essential for the onset and progression of mitosis. Aurora members share a similar protein structure and kinase activity, but exhibit distinct cellular and subcellul...

    Authors: Estelle Willems, Matthias Dedobbeleer, Marina Digregorio, Arnaud Lombard, Paul Noel Lumapat and Bernard Rogister

    Citation: Cell Division 2018 13:7

    Content type: Review

    Published on:

  15. Live-cell fluorescence microscopy (LCFM) is a powerful tool used to investigate cellular dynamics in real time. However, the capacity to simultaneously measure DNA content in cells being tracked over time rema...

    Authors: Cecil J. Gomes, Michael W. Harman, Sara M. Centuori, Charles W. Wolgemuth and Jesse D. Martinez

    Citation: Cell Division 2018 13:6

    Content type: Methodology

    Published on:

  16. Inosine monophosphate dehydrogenase (IMPDH), the rate-limiting enzyme in de novo GTP biosynthesis, plays an important role in cell metabolism and proliferation. It has been demonstrated that IMPDH can aggregat...

    Authors: Gerson Dierley Keppeke, Chia Chun Chang, Min Peng, Li-Yu Chen, Wei-Cheng Lin, Li-Mei Pai, Luis Eduardo Coelho Andrade, Li-Ying Sung and Ji-Long Liu

    Citation: Cell Division 2018 13:5

    Content type: Research

    Published on:

  17. Kinesin superfamily proteins are microtubule-based molecular motors essential for the intracellular transport of various cargos, including organelles, proteins, and RNAs. However, their exact roles during mamm...

    Authors: Yan Xie, Minghui Cheng, Shan Lu, Qilong Yuan, Dongyu Yang, Ying Chen, Chen Pan, Yurong Qiu and Bo Xiong

    Citation: Cell Division 2018 13:4

    Content type: Research

    Published on:

  18. Just like all matter, proteins can also switch between gas, liquid and solid phases. Protein phase transition has claimed the spotlight in recent years as a novel way of how cells compartmentalize and regulate...

    Authors: Steven Boeynaems, Peter Tompa and Ludo Van Den Bosch

    Citation: Cell Division 2018 13:1

    Content type: Commentary

    Published on:

  19. Cyclin-dependent kinases (CDKs) are key regulators of both cell cycle progression and transcription. Since dysregulation of CDKs is a frequently occurring event driving tumorigenesis, CDKs have been tested ext...

    Authors: Hana Paculová and Jiří Kohoutek

    Citation: Cell Division 2017 12:7

    Content type: Review

    Published on:

  20. The G1-S phase transition is critical to maintaining proliferative control and preventing carcinogenesis. The retinoblastoma tumor suppressor is a key regulator of this step in the cell cycle.

    Authors: Michael J. Thwaites, Matthew J. Cecchini, Srikanth Talluri, Daniel T. Passos, Jasmyne Carnevale and Frederick A. Dick

    Citation: Cell Division 2017 12:3

    Content type: Research

    Published on:

  21. Genetic screens have identified many novel components of various biological processes, such as components required for cell cycle and cell division. While forward genetic screens typically generate unstructure...

    Authors: Maximilian Billmann and Michael Boutros

    Citation: Cell Division 2017 12:2

    Content type: Commentary

    Published on:

  22. Correct chromosome segregation depends on the sister chromatid cohesion complex. The essential, evolutionarily conserved regulatory protein Irr1/Scc3, is responsible for the complex loading onto DNA and for it...

    Authors: Piotr Kowalec, Jan Fronk and Anna Kurlandzka

    Citation: Cell Division 2017 12:1

    Content type: Research

    Published on:

  23. Recent experiments regarding Ndc80/Hec1 in force generation at kinetochores for chromosome motions have prompted speculation about possible models for interactions between positively charged molecules at kinet...

    Authors: L. John Gagliardi and Daniel H. Shain

    Citation: Cell Division 2016 11:14

    Content type: Commentary

    Published on:

    The Erratum to this article has been published in Cell Division 2017 12:4

  24. The Notch signaling pathway is a reiteratively used cell to cell communication pathway that triggers pleiotropic effects. The correct regulation of the pathway permits the efficient regulation of genes involve...

    Authors: Humberto Contreras-Cornejo, Germán Saucedo-Correa, Javier Oviedo-Boyso, Juan José Valdez-Alarcón, Víctor Manuel Baizabal-Aguirre, Marcos Cajero-Juárez and Alejandro Bravo-Patiño

    Citation: Cell Division 2016 11:12

    Content type: Review

    Published on:

  25. Tumor response to immunotherapy is the consequence of a concerted crosstalk between cytokines and effector cells. Interferon gamma (IFNγ) is one of the common cytokines coordinating tumor immune response and t...

    Authors: Siraj M. El Jamal, Erin B. Taylor, Zakaria Y. Abd Elmageed, Abdulhadi A. Alamodi, Denis Selimovic, Abdulaziz Alkhateeb, Matthias Hannig, Sofie Y. Hassan, Simeon Santourlidis, Paul L. Friedlander, Youssef Haikel, Srinivasan Vijaykumar, Emad Kandil and Mohamed Hassan

    Citation: Cell Division 2016 11:11

    Content type: Research

    Published on:

  26. The transition from mitotic cell division to meiotic development in S. cerevisiae requires induction of a transient transcription program that is initiated by Ime1-dependent destruction of the repressor Ume6. Alt...

    Authors: Stephen J. Kim and Randy Strich

    Citation: Cell Division 2016 11:10

    Content type: Research

    Published on:

    The Erratum to this article has been published in Cell Division 2017 12:5

  27. Cullin-RING ligases (CRLs), the largest E3 ubiquitin ligase family, promote ubiquitination and degradation of various cellular key regulators involved in a broad array of physiological and pathological process...

    Authors: Danrui Cui, Xiufang Xiong and Yongchao Zhao

    Citation: Cell Division 2016 11:8

    Content type: Review

    Published on:

  28. TBX3, a member of the T-box family of transcription factors, is essential in development and has emerged as an important player in the oncogenic process. TBX3 is overexpressed in several cancers and has been s...

    Authors: Tarryn Willmer, Shannagh Hare, Jade Peres and Sharon Prince

    Citation: Cell Division 2016 11:6

    Content type: Research

    Published on:

  29. PTMs (posttranslational modifications) such as ubiquitylation, sumoylation, acetylation and protein methylation are pivotal modifiers that determine the activation, deactivation or subcellular localization of ...

    Authors: Mingjing He, Zhuan Zhou, Anil A. Shah, Yang Hong, Qianming Chen and Yong Wan

    Citation: Cell Division 2016 11:4

    Content type: Review

    Published on:

  30. The suppressor of cytokine signaling (SOCS) box consists of the BC box and the cullin 5 (Cul5) box, which interact with Elongin BC and Cul5, respectively. SOCS box-containing proteins have ubiquitin ligase act...

    Authors: Fumihiko Okumura, Akiko Joo-Okumura, Kunio Nakatsukasa and Takumi Kamura

    Citation: Cell Division 2016 11:1

    Content type: Review

    Published on:

  31. Curcumin has long been known to posses medicinal properties and recent scientific studies have shown its efficacy in treating cancer. Curcumin is now considered to be a promising anti-cancer agent and studies ...

    Authors: Sayantan Bose, Abir Kumar Panda, Shravanti Mukherjee and Gaurisankar Sa

    Citation: Cell Division 2015 10:6

    Content type: Review

    Published on:

  32. Cullin-RING ubiquitin ligases (CRLs) are regulated by neddylation, which is a post translation modification of the Cullin family proteins. Neddylation of Cul1 activates the ligase through some means of biochem...

    Authors: Gil Bornstein and Chagai Grossman

    Citation: Cell Division 2015 10:5

    Content type: Research

    Published on:

  33. The ubiquitin family member Sumo has important functions in many cellular processes including DNA repair, transcription and cell division. Numerous studies have shown that Sumo is essential for maintaining cel...

    Authors: Jorrit M. Enserink

    Citation: Cell Division 2015 10:4

    Content type: Review

    Published on:

  34. The cyclin E oncogene activates CDK2 to drive cells from G1 to S phase of the cell cycle to commence DNA replication. It coordinates essential cellular functions with the cell cycle including histone biogenesis, ...

    Authors: Samuel Rogers, Brian S Gloss, Christine S Lee, Claudio Marcelo Sergio, Marcel E Dinger, Elizabeth A Musgrove, Andrew Burgess and Catherine Elizabeth Caldon

    Citation: Cell Division 2015 10:1

    Content type: Short report

    Published on:

  35. Recent experiments revealing nanoscale electrostatic force generation at kinetochores for chromosome motions have prompted models for interactions between positively charged molecules in kinetochores and negat...

    Authors: Lucian John Gagliardi and Daniel H Shain

    Citation: Cell Division 2014 9:5

    Content type: Commentary

    Published on:

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